Sega Retro has an excellent page covering the history of the Sega Mega Drive in great detail, it is highly recommended that you read this before anything else:
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History of the Sega Mega Drive - Sega Retro
Find out about the history of the SEGA Mega Drive in this excellent post
In order for game developers to create software for the SEGA Mega Drive, they had the choice of a number of different development hardware to purchase, or they could go it alone and create their own hardware. To find out more check out the post below.
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Sega Mega Drive (Genesis) Development Kit Hardware
For information about SEGA's Mega Drive development hardware check out this post.
The Youtuber Game Hut has a series of tutorials on Sega Mega drive programming. Part 1:
Part 2:
